A new MR imaging index for differentiation of progressive supranuclear palsy-parkinsonism from Parkinson's disease

Highlights

• Distinguishing PSP-P from PD is challenging in the early stages of the disease.
• Few data exist on the usefulness of MRPI for diagnosing PSP-P patients.
• MRPI 2.0 is a new version of MRPI which includes the 3rd ventricular width
• MRPI 2.0 accurately differentiated patients with PSP-P from those with PD.
• MRPI 2.0 accurately diagnosed PSP-P in the absence of vertical ocular palsy.

Reference: Quattrone A, Morelli M, Nigro S, Quattrone A, Vescio B, Arabia G, Nicoletti G,Nisticò R, Salsone M, Novellino F, Barbagallo G, Le Piane E, Pugliese P, Bosco D, Vaccaro MG, Chiriaco C, Sabatini U, Vescio V, Stanà C, Rocca F, Gullà D, Caracciolo M. A new MR imaging index for differentiation of progressive supranuclear palsy-parkinsonism from Parkinson's disease. Parkinsonism Relat Disord. 2018 Sep;54:3-8. doi: 10.1016/j.parkreldis.2018.07.016